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bcr-v-abl Oncogene

《英文msh词典》bcr-v-abl Oncogene
[入口词] bcr-v-abl Oncogene
[主题词] Genes,abl
[英文释义] Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.

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